BPC-157
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What is BPC-157?
BPC-157 is a synthetic pentadecapeptide (15 amino acids) derived from a protective protein found in human gastric juice. It's known for its remarkable healing properties and is extensively researched for tissue repair, inflammation reduction, and gastrointestinal protection. Not FDA approved and prohibited by WADA (added 2022) under SO: Non-Approved Substances - no TUE available for athletes.
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Key Benefits
Accelerated healing of tendons, ligaments, muscles, bones, and localised tissue repair.
Superior bioavailability for targeted healing with anti-inflammatory effects. -
Mechanism of Action
Injectable BPC-157 provides direct tissue targeting and higher local concentrations. Promotes angiogenesis (formation of new blood vessels), enhances collagen synthesis, modulates growth factor expression, and provides localised protection against tissue damage.
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Typical Dose
250-500 mcg
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Frequency
1-2x daily
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Injection Sites
Belly, thigh, arm (near injury for localized healing)
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Best Timing
Empty stomach preferred
Injectable BPC-157 is most effective on empty stomach. For injury healing, inject as close to the injury site as possible (subcutaneous). Rotate injection sites to prevent tissue irritation.
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Effects Timeline
1-3 weeks for healing, 3-7 days for inflammation
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Storage
Fridge 2-6°C
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Cycle Length
4-12 weeks
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Molecular Information
Molecular Weight
1,419.53 Da
Chain Length
15 amino acids
Amino Acid Sequence
Gly-Lys-Pro-Pro-Pro-Gly-Lys-Pro-Ala-Asp-Asp-Ala-Gly-Leu-Val -
Disclaimer
Commonly cycled 4-12 weeks on, 4+ weeks off in research protocols. No loading phase is typically used. Tapering is generally not reported as necessary, though some gradually reduce over the final week on longer
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Research Indications
Wound Healing -Most Effective
Tendon Healing
Accelerated tendon-to-bone healing and improved biomechanical properties in injury models. Most effective with localized injection.
Muscle Recovery
Enhanced muscle healing and reduced recovery time following crush injuries and surgical procedures with direct tissue targeting.
Angiogenesis
Promotes blood vessel formation and improves vascularization in healing tissues through localized delivery.
Neurological- Effective
Neuroprotection
Protective effects against various neurotoxic agents and ischemic brain injury models with systemic administration.
Spinal Cord Injury
Improved functional recovery and reduced tissue damage in spinal cord injury studies via injection.
Peripheral Nerves
Enhanced peripheral nerve regeneration and functional recovery after injury with localized treatment. -
What to Expect
* Week 1-2: Reduced inflammation and pain at injection site
* Week 2-4: Improved healing rate and tissue repair
* Week 4-8: Maximum localised healing benefits
* Side effects: Mild injection site redness or irritation
* Most effective for: Tendon, ligament, muscle injuries -
Side Effects & Safety
May cause mild injection site reactions
Consult doctor if on blood thinners due to
angiogenesis effects
Not recommended during pregnancy or breastfeeding
WADA prohibited (SO: Non-Approved
Substances) - not for competitive athletes